In part, the beneficial effect of selenium on genomic stability is associated with the antioxidation effect of selenoproteins such as GPXs and TXNRDs, which remove ROS before they cause DNA damage 134
By targeting the FOXO4-p53 protein interaction responsible for keeping these damaged cells alive, FOXO4-DRI restores healthy cellular turnover, making it one of the most promising compounds in modern longevity and anti-aging research
F.PapaleM.LicariA.SalpietroC.Miraglia del GiudiceM.et al
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Adapted from Laidlaw and Cyster, Nat Rev Immunol
First identified in human plasma in 1973 by Loren Pickart, this human tripeptide ghk cu is naturally present in plasma, saliva, and urine, with levels declining significantly between ages 20 and 60, a pattern that correlates directly with reduced tissue repair capacity and visible signs of skin aging